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High cholesterol could be dangerous, along with the deposits of other substances, such as fat, on the walls of the arteries. These plaques can reduce blood flow through the arteries, which in turn can cause complications such as chest pain, blood clots, and heart attack. Hence, there is a need for an efficient way to measure the concentration of cholesterol in blood vessels with great accuracy to predict its risk on health. The present study aims to measure the concentration of cholesterol and track it accurately in the blood vessels using an ultrasound pressure sensor, which detects the concentration of cholesterol and produces a pressure field around its surface that is directly proportional to the concentration. This field can be tracked by ultrasound. In this study, the experiments conducted involved the insertion of aluminum nanoparticles, which represent a pressure sensor coated with a massless piezoelectric …