Authors
Gerard Nkeunen, Tsafack Takadong Julie Judith, Simo Gustave, Betrand Ayuk Tambe, Ayangma Celestin Roger, Tume Christopher Bonglavnyuy
Publication date
2019/12/14
Journal
International Journal of Biochemistry Research & Review
Volume
28
Issue
4
Pages
1-11
Description
Aims
A healthy skeletal system with strong bones is essential to overall health. This study aimed to assess lifestyle and bone’s biomarkers of women.
Study Design
This was a cross-sectional study.
Place and Duration of Study
The enrollment took place at the Yaounde Military Hospital from November 2016 to July 2017.
Methodology
A set of 105 postmenopausal and 127 premenopausal participants were enrolled from November 2016 to July 2017 in Yaounde. Their physical activities level was evaluated using a questionnaire. Sunlight exposure between 10:00AM and 4:00PM was assessed. Colorimetric methods were used to evaluate calcium, albumin, and alkaline phosphatase activity in plasma. These parameters were then compared within year since menopause (YSM) and osteoporosis risk assessment instrument (ORAI) sub-groups.
Results
13.4% participants were moderately active. Only 22.8% participants had at least 30 minutes sun exposure daily. A multivariable analysis of demographic, lifestyle, biochemical characteristic revealed age, BMI, albumin and calcium were the main factors that influenced bone health among our participants. A significant difference of calcium concentration was found between the two groups whereas albumin was significantly higher in premenopausal than postmenopausal. Albumin was the only variable with a significant difference in the YSM sub-groups while only calcium was non-significantly higher among the ORAI sub-groups.
Conclusion
Elevated plasma level of calcium, albumin and alkaline phosphatase could be indicators of high bone turnover.
Scholar articles
G Nkeunen, TTJ Judith, S Gustave, BA Tambe… - International Journal of Biochemistry Research & …, 2019