Authors
Karla María Tamez-Torres, Pedro Torres-González, Francisco Leal-Vega, Ariana García-Alderete, Norma Irene López García, Raquel Mendoza-Aguilar, Arturo Galindo-Fraga, Miriam Bobadilla-del Valle, Alfredo Ponce de León, José Sifuentes-Osornio
Publication date
2017/12/1
Journal
International Journal of Infectious Diseases
Volume
65
Pages
44-49
Publisher
Elsevier
Description
Objectives
To describe the clinical characteristics, outcomes, and factors associated with Clostridium difficile infection (CDI) due to ribotype 027 (RT027) and recurrence, including an outbreak period, with transition to endemicity.
Methods
A case–control study was performed. Clinical and demographic data were collected for patients with CDI during the period January 2008 to December 2015. Ribotyping of the isolates and PCR for toxin A, B, and binary were performed.
Results
Among 324 episodes of CDI, 27.7% were caused by RT027. Previous fluoroquinolone use (odds ratio (OR) 1.79, 95% confidence interval (CI) 1.01–3.17), previous gastrointestinal endoscopy (OR 2.17, 95% CI 1.29–3.65), chemotherapy (OR 0.43, 95% CI 0.19–0.95), and total enteral nutrition (OR 0.42, 95% CI 0.18–0.97) were associated with RT027. Age >65 years (OR 2.05, 95% CI 1.02–4.10), severe initial episode (OR 3.35, 95% CI 1.60–6 …
Scholar articles
KM Tamez-Torres, P Torres-González, F Leal-Vega… - International Journal of Infectious Diseases, 2017