Authors
Ioannis S Vlachos, Nikos Kostoulas, Thanasis Vergoulis, Georgios Georgakilas, Martin Reczko, Manolis Maragkakis, Maria D Paraskevopoulou, Kostantinos Prionidis, Theodore Dalamagas, Artemis G Hatzigeorgiou
Publication date
2012/7/1
Journal
Nucleic acids research
Volume
40
Issue
W1
Pages
W498-W504
Publisher
Oxford University Press
Description
MicroRNAs (miRNAs) are key regulators of diverse biological processes and their functional analysis has been deemed central in many research pipelines. The new version of DIANA-miRPath web server was redesigned from the ground-up. The user of DNA Intelligent Analysis (DIANA) DIANA-miRPath v2.0 can now utilize miRNA targets predicted with high accuracy based on DIANA-microT-CDS and/or experimentally verified targets from TarBase v6; combine results with merging and meta-analysis algorithms; perform hierarchical clustering of miRNAs and pathways based on their interaction levels; as well as elaborate sophisticated visualizations, such as dendrograms or miRNA versus pathway heat maps, from an intuitive and easy to use web interface. New modules enable DIANA-miRPath server to provide information regarding pathogenic single nucleotide polymorphisms (SNPs) in miRNA target sites …
Total citations
201220132014201520162017201820192020202120222023202443462110123754043353426119
Scholar articles
IS Vlachos, N Kostoulas, T Vergoulis, G Georgakilas… - Nucleic acids research, 2012