Authors
Shirin Aliabadi, Philip Anyanwu, Elizabeth Beech, Elita Jauneikaite, Peter Wilson, Russell Hope, Azeem Majeed, Berit Muller-Pebody, Céire Costelloe
Publication date
2021/12/1
Journal
The Lancet Infectious Diseases
Volume
21
Issue
12
Pages
1689-1700
Publisher
Elsevier
Description
Background
Antimicrobial resistance is a major global health concern, driven by overuse of antibiotics. We aimed to assess the effectiveness of a national antimicrobial stewardship intervention, the National Health Service (NHS) England Quality Premium implemented in 2015–16, on broad-spectrum antibiotic prescribing and Escherichia coli bacteraemia resistance to broad-spectrum antibiotics in England.
Methods
In this quasi-experimental, ecological, data linkage study, we used longitudinal data on bacteraemia for patients registered with a general practitioner in the English National Health Service and patients with E coli bacteraemia notified to the national mandatory surveillance programme between Jan 1, 2013, and Dec 31, 2018. We linked these data to data on antimicrobial susceptibility testing of E coli from Public Health England's Second-Generation Surveillance System. We did an ecological analysis …
Total citations
Scholar articles
S Aliabadi, P Anyanwu, E Beech, E Jauneikaite… - The Lancet Infectious Diseases, 2021