Authors
Nan Zhang, Haiqing Zhang, XU Zhang, Bingchang Zhang, Furong Wang, Chenggang Wang, Meng Zhao, Chunxiao Yu, Ling Gao, Jiajun Zhao, Qingbo Guan
Publication date
2014/4
Journal
European journal of endocrinology
Volume
170
Issue
4
Pages
487-494
Publisher
Oxford University Press
Description
Objective
To evaluate the relationship between serum total testosterone (TT) level and lipid profile after adjusting for some traditional confounding factors, free thyroid hormones and TSH in Chinese men.
Methods
This was a retrospective study based on an epidemiological investigation including 11 000 subjects. Bivariate and partial correlation analysis, multiple linear regression analysis, and a general linear model were used to assess the influence of TT on the lipid profile. Additionally, the odds ratios (ORs) (95% CIs) for hypertriglyceridemia and low HDL-C in relation to TT categories were calculated using logistic regression analysis.
Results
A total of 4114 subjects whose mean age was 56.04±8.75 years were finally analyzed. There was a significant linear trend toward lower total cholesterol (TC), lower triglycerides (TG), and higher HDL-C with …
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