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Traditionally, life cycle assessment (LCA) is mostly concerned with product design and hardly considers large systems, such as buildings, as a whole. Though, by limiting LCA to building materials or building components, boundary conditions, such as thermal comfort and indoor air quality, cannot be taken into account. The life cycle inventory (LCI) model presented in this paper forms part of a global methodology that combines advanced optimisation techniques, LCI and cost-benefit assessment to optimise low energy buildings simultaneously for energy, environmental impact and costs without neglecting the boundary conditions for thermal comfort, indoor air quality and legal requirements for energy performance. This paper first outlines the goal and scope of the LCI. Then, the partial inventory models as well as the overall building inventory model are presented. Finally, the LCI results are shown and discussed for …