Authors
Jun Xia, Muhammad R Chatni, Konstantin Maslov, Zijian Guo, Kun Wang, Mark Anastasio, Lihong V Wang
Publication date
2012/5/1
Journal
Journal of biomedical optics
Volume
17
Issue
5
Pages
050506-050506
Publisher
Society of Photo-Optical Instrumentation Engineers
Description
We report a novel small-animal whole-body imaging system called ring-shaped confocal photoacoustic computed tomography (RC-PACT). RC-PACT is based on a confocal design of free-space ring-shaped light illumination and 512-element full-ring ultrasonic array signal detection. The free-space light illumination maximizes the light delivery efficiency, and the full-ring signal detection ensures a full two-dimensional view aperture for accurate image reconstruction. Using cylindrically focused array elements, RC-PACT can image a thin cross section with 0.10 to 0.25 mm in-plane resolutions and acquisition time. By translating the mouse along the elevational direction, RC-PACT provides a series of cross-sectional images of the brain, liver, kidneys, and bladder.
Total citations
Scholar articles
J Xia, MR Chatni, K Maslov, Z Guo, K Wang… - Journal of biomedical optics, 2012