Authors
EM1 Camacho, IT Huhtaniemi, TW O'neill, JD Finn, SR Pye, DM Lee, A Tajar, G Bartfai, Steven Boonen, FF Casanueva, Gianni Forti, Aleksander Giwercman, TS Han, K Kula, B Keevil, ME Lean, N Pendleton, M Punab, Dirk Vanderschueren, FCW Wu, EMAS Group
Publication date
2013/3
Journal
European journal of endocrinology
Volume
168
Issue
3
Pages
445-455
Publisher
Oxford University Press
Description
Objective
Health and lifestyle factors are associated with variations in serum testosterone levels in ageing men. However, it remains unclear how age-related changes in testosterone may be attenuated by lifestyle modifications. The objective was to investigate the longitudinal relationships between changes in health and lifestyle factors with changes in hormones of the reproductive endocrine axis in ageing men.
Design
A longitudinal survey of 2736 community-dwelling men aged 40–79 years at baseline recruited from eight centres across Europe. Follow-up assessment occurred mean (±s.d.) 4.4±0.3 years later.
Results
Paired testosterone results were available for 2395 men. Mean (±s.d.) annualised hormone changes were as follows: testosterone −0.1±0.95 nmol/l; free testosterone (FT) −3.83±16.8 pmol/l; sex hormone-binding globulin (SHBG) 0.56±2 …
Scholar articles
EM Camacho, IT Huhtaniemi, TW O'neill, JD Finn… - European journal of endocrinology, 2013