Authors
SR Pye, IT Huhtaniemi, JD Finn, DM Lee, TW O'Neill, A Tajar, György Bártfai, S Boonen, FF Casanueva, Gianni Forti, Aleksander Giwercman, TS Han, K Kula, ME Lean, N Pendleton, M Punab, MK Rutter, D Vanderschueren, FCW Wu, EMAS Study Group
Publication date
2014/4/1
Journal
The Journal of Clinical Endocrinology & Metabolism
Volume
99
Issue
4
Pages
1357-1366
Publisher
Oxford University Press
Description
Context
Late-onset hypogonadism (LOH) has recently been defined as a syndrome in middle-aged and elderly men reporting sexual symptoms in the presence of low T. The natural history of LOH, especially its relationship to mortality, is currently unknown.
Objective
The aim of this study was to clarify the associations between LOH, low T, and sexual symptoms with mortality in men.
Design, Setting, and Participants
Prospective data from the European Male Aging Study (EMAS) on 2599 community-dwelling men aged 40–79 years in eight European countries was used for this study.
Main Outcome Measure(s)
All-cause, cardiovascular, and cancer-related mortality was measured.
Results
One hundred forty-seven men died during a median follow-up of 4.3 years. Fifty-five men (2.1%) were identified as having LOH (31 …
Scholar articles
SR Pye, IT Huhtaniemi, JD Finn, DM Lee, TW O'Neill… - The Journal of Clinical Endocrinology & Metabolism, 2014