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One of the global community’s most significant contemporary challenges is the need to satisfy growing energy demand, while simultaneously achieving very significant reductions in the greenhouse gas (GHG) emissions associated with the production, delivery, and consumption of energy. The energy sector is transforming via the convergence of power, transportation, and industrial sectors and inter-sectoral integration. To assess the level of decarbonization achieved through this change, one needs to study the carbon footprint of the energy system as a whole. Here, we present a novel, system-scale energy analysis tool, the Sustainable Energy System Analysis Modelling Environment (SESAME), to assess the pathway- and system-level GHG emissions of today’s changing energy system. The underlying analytic tool constitutes more than a thousand individual energy pathways. SESAME provides a consistent …