Authors
Kirsten M Fiest, Khara M Sauro, Samuel Wiebe, Scott B Patten, Churl-Su Kwon, Jonathan Dykeman, Tamara Pringsheim, Diane L Lorenzetti, Nathalie Jetté
Publication date
2017/1/17
Source
Neurology
Volume
88
Issue
3
Pages
296-303
Publisher
Lippincott Williams & Wilkins
Description
Objective
To review population-based studies of the prevalence and incidence of epilepsy worldwide and use meta-analytic techniques to explore factors that may explain heterogeneity between estimates.
Methods
The Preferred Reporting Items for Systematic Reviews and Meta-Analyses standards were followed. We searched MEDLINE and EMBASE for articles published on the prevalence or incidence of epilepsy since 1985. Abstract, full-text review, and data abstraction were conducted in duplicate. Meta-analyses and meta-regressions were used to explore the association between prevalence or incidence, age group, sex, country level income, and study quality.
Results
A total of 222 studies were included (197 on prevalence, 48 on incidence). The point prevalence of active epilepsy was 6.38 per 1,000 persons (95% confidence interval [95% CI] 5.57–7.30), while the lifetime prevalence was 7.60 per 1,000 …
Scholar articles
Prevalence and incidence of epilepsy: a systematic review and meta-analysis of international studies
KM Fiest, KM Sauro, S Wiebe, SB Patten, CS Kwon… - Neurology, 2017