Authors
P LAI, N Yusoff, Z Taha, M Arshad, V Chongsuvivatwong, S Aljunid, Nordin Bin Rusli, A Anees, A Zulkifli, M Hashim Mohd, A Azni, N Kumaraswamy, A Sharmini Liza, B Zilfalil, A Dicom, S Draman, M Merchant, T Arif, M Harmy, S Ismail, S Singh Jasmit, L Teh, R Ismail, J Amir, S Ho, N Shamsuddin, R Jaafar, A Ismail, T Kek, K Johari, L Yee, Z Alwi, L Leng, O Hayati Nor, M Madhavan, B Hamdi, M Norazlinda, I Wahida Farah, B Lokman, B Aminuddin, B Ruszymah, A Rehman, A Rahman, L Naing, A Ayu, A Samsudin, I Khairani, A Azlina, N Ahmad Shah Nik, M Isa, K Seman, S Noor, N Ghaffar, W Yusuff, Z Hanafiah, N Maning, N Nik Lah Zuky, N Hussain Nik, M Johari Radzi, S Nordin, N Hussain, M Sidek, S Ramli, M Sarhan, Z Zainuddin, M Musa, G Kaur, A Majumder, A Rahim, H Emdadul, R Ja’afar, A Barman, A Salam, M Rosidah, M Wahab, M Khairi, S Suhaimi Din, H Shahid, D Latifah, A Al-Safi, A Hamzah, W Faisham, K Hoari, B Biswal, N Othman, I Shuaib, W Zulmi, A Shahrulazua, M Norazman, A Halim, A Sallehuddin, S Suresh, A Saim Mat, M Yatiban, T Muzaffar, N Rizal Nik, A Azman Nurul, Z Zahari Ahmad, M Bhavaraju, N Ahmad, A Noorazizah, M Latifah, A Min Nik, V Bhavaraju, Z Rozaimey, K Kamarulasikin, H Kareem Abdul, H Shuaib, N Azman, M Rahman, S Satari, A Kifle, S Khan, M Hamza, D Sohaimi, S Hassan, I Ghani, R Ramli, B Abdullah, Z Idzwan Mohd, M Iskandar Mohd, A Rashidi, W Aasim Wan, M Nasir, A Kamarul, N Ariff Nik, A Ariff, M Abdullah, A Pany, J Salmah, J Abdullah, I Zamzuri, Ralib Razali bin Md Ahmad, A Leow, Z Wan, F Ali, K Amla, A Dorai, M Hanafi, A Saedah, J Kamarudin, P Gnandev, S Swaram, N Abdullah Nik, O Hamizad, O Mahamarowi, H ShamsulKamalrujan, G Ghazaimie, T Norizan, A Nizar
Publication date
2003/7
Journal
The Malaysian journal of medical sciences: MJMS
Volume
10
Issue
2
Pages
103-186
Publisher
School of Medical Sciences, Universiti Sains Malaysia
Description
The role of genetics in medicine has been recognized for many years and further genetic research is to understand the gene functions and the gene interactions with the environment. These were made easier with the launching of the Human Genome Project whose aim is to decipher and decode the entire human genome and to understand their structure and functions. It will be beneficial to the biomedical research and the applications of genomic knowledge in the practice of medicine. The successful completion of the Human Genome Project has shown an impact on medicine. It supports the research to unravel the mysterious of human biology and provide wealth of new information for the clinicians to understand the diseases. These will help to develop new technologies for the diagnosis, prevention, and treatment of single gene disorders, complex disorders with the promise for new therapies. Large scale genotyping and short nucleotide polymorphisms (SNP’s) discoveries have shown why some individuals are susceptible to certain disease like diabetes, cancer, or suffers serious drug reactions. This knowledge of the genetic differences in an individual can change the management and treatment of the disease based on personal genetic make-ups such as drug response, influence and adverse reactions. This approach will lead to a personalized medicine in a near future. As such early identification and detection of pre-symptomatic individual at-risk as in cardiovascular medicine, hematology, oncology, gastroenterology, hepatology, psychiatry and psychology are in highly needed. Thus the challenges for the efficient incorporating of genomic …
Scholar articles
P LAI, N Yusoff, Z Taha, M Arshad… - The Malaysian journal of medical sciences: MJMS, 2003