Authors
Swati A Kulkarni, Kirti Kulkarni, David Schacht, Sonya Bhole, Ingrid Reiser, Hiroyuki Abe, Jean Bao, Kevin Bethke, Nora Hansen, Nora Jaskowiak, Seema A Khan, Jennifer Tseng, Buxin Chen, Jennifer Pincus, Jeffrey Mueller, Lauren Schulte, Bazil LaBomascus, Zheng Zhang, Dan Xia, Xiaochuan Pan, Christian Wietholt, Dimple Modgil, David Lester, Li Lan, Bidur Bohara, Xiao Han
Publication date
2021/10
Journal
Annals of surgical oncology
Volume
28
Pages
5513-5524
Publisher
Springer International Publishing
Description
Background
Two-dimensional (2D) specimen radiography (SR) and tomosynthesis (DBT) for breast cancer yield data that lack high-depth resolution. A volumetric specimen imager (VSI) was developed to provide full-3D and thin-slice cross-sectional visualization at a 360° view angle. The purpose of this prospective trial was to compare VSI, 2D SR, and DBT interpretation of lumpectomy margin status with the final pathologic margin status of breast lumpectomy specimens.
Methods
The study enrolled 200 cases from two institutions. After standard imaging and interpretation was performed, the main lumpectomy specimen was imaged with the VSI device. Image interpretation was performed by three radiologists after surgery based on VSI, 2D SR, and DBT. A receiver operating characteristic (ROC) curve was created for each method. The area under the …
Total citations
Scholar articles
SA Kulkarni, K Kulkarni, D Schacht, S Bhole, I Reiser… - Annals of surgical oncology, 2021
S Kulkarni, I Reiser, D Schacht, S Bhole, K Kulkarni… - ANNALS OF SURGICAL ONCOLOGY, 2021