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Comparison of multiple hydrologic indicators, derived from independent data sources and modeling approaches, may improve confidence in signals of emerging drought, particularly during periods of rapid onset. This paper compares the evaporative stress index (ESI)—a diagnostic fast-response indicator describing evapotranspiration (ET) deficits derived within a thermal remote sensing energy balance framework—with prognostic estimates of soil moisture (SM), ET, and runoff anomalies generated with the North American Land Data Assimilation System (NLDAS). Widely used empirical indices based on thermal remote sensing [vegetation health index (VHI)] and precipitation percentiles [standardized precipitation index (SPI)] were also included to assess relative performance. Spatial and temporal correlations computed between indices over the contiguous United States were compared with historical …