Authors
Svein Linge, Joakim Sundnes, Monica Hanslien, Glenn Terje Lines, Aslak Tveito
Publication date
2009/5/28
Source
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Volume
367
Issue
1895
Pages
1931-1950
Publisher
The Royal Society
Description
Knowledge of cardiac electrophysiology is efficiently formulated in terms of mathematical models. However, most of these models are very complex and thus defeat direct mathematical reasoning founded on classical and analytical considerations. This is particularly so for the celebrated bidomain model that was developed almost 40 years ago for the concurrent analysis of extra- and intracellular electrical activity. Numerical simulations based on this model represent an indispensable tool for studying electrophysiology. However, complex mathematical models, steep gradients in the solutions and complicated geometries lead to extremely challenging computational problems. The greatest achievement in scientific computing over the past 50 years has been to enable the solving of linear systems of algebraic equations that arise from discretizations of partial differential equations in an optimal manner, i.e. such that …
Total citations
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Scholar articles
S Linge, J Sundnes, M Hanslien, GT Lines, A Tveito - Philosophical Transactions of the Royal Society A …, 2009