Authors
Angela Cánovas, Raquel Quintanilla, Marcel Amills, Ramona N Pena
Publication date
2010/12
Journal
BMC genomics
Volume
11
Pages
1-15
Publisher
BioMed Central
Description
Background
Selection for increasing intramuscular fat content would definitively improve the palatability and juiciness of pig meat as well as the sensorial and organoleptic properties of cured products. However, evidences obtained in human and model organisms suggest that high levels of intramuscular fat might alter muscle lipid and carbohydrate metabolism. We have analysed this issue by determining the transcriptomic profiles of Duroc pigs with divergent phenotypes for 13 fatness traits. The strong aptitude of Duroc pigs to have high levels of intramuscular fat makes them a valuable model to analyse the mechanisms that regulate muscle lipid metabolism, an issue with evident implications in the elucidation of the genetic basis of human metabolic diseases such as obesity and insulin resistance.
Results
Muscle gene expression profiles of 68 Duroc …
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