Authors
International Glossina Genome Initiative, Geoffrey M Attardo, Patrick P Abila, Joanna E Auma, Aaron A Baumann, Joshua B Benoit, Corey L Brelsfoard, José MC Ribeiro, James A Cotton, Daphne QD Pham, Alistair C Darby, Jan Van Den Abbeele, David L Denlinger, Linda M Field, Steven RG Nyanjom, Michael W Gaunt, Dawn L Geiser, Ludvik M Gomulski, Lee R Haines, Immo A Hansen, Jeffery W Jones, Caleb K Kibet, Johnson K Kinyua, Denis M Larkin, Michael J Lehane, Rita VM Rio, Sandy J Macdonald, Rosaline W Macharia, Anna R Malacrida, Heather G Marco, Kevin K Marucha, Daniel K Masiga, Megan E Meuti, Paul O Mireji, George FO Obiero, Jacobus JO Koekemoer, Chinyere K Okoro, Irene A Omedo, Victor C Osamor, Apollo SP Balyeidhusa, Justin T Peyton, David P Price, Michael A Quail, Urvashi N Ramphul, Neil D Rawlings, Michael A Riehle, Hugh M Robertson, Mandy J Sanders, Maxwell J Scott, Zahra Jalali Sefid Dashti, Anna K Snyder, Tulika P Srivastava, Eleanor J Stanley, Martin T Swain, Daniel ST Hughes, Aaron M Tarone, Todd D Taylor, Erich L Telleria, Gavin H Thomas, Deirdre P Walshe, Richard K Wilson, Joy J Winzerling, Alvaro Acosta-Serrano, Serap Aksoy, Peter Arensburger, Martin Aslett, Rosemary Bateta, Alia Benkahla, Matthew Berriman, Kostas Bourtzis, Jelle Caers, Guy Caljon, Alan Christoffels, Marco Falchetto, Markus Friedrich, Shuhua Fu, Gerd Gäde, George Githinji, Richard Gregory, Neil Hall, Gordon Harkins, Masahira Hattori, Christiane Hertz-Fowler, Winston Hide, Wanqi Hu, Tadashi Imanishi, Noboru Inoue, Mario Jonas, Yoshihiro Kawahara, Mathurin Koffi, Adele Kruger, Daniel Lawson, Stella Lehane, Heikki Lehväslaiho, Thiago Luiz, Mmule Makgamathe, Imna Malele, Oliver Manangwa, Lucien Manga, Karyn Megy, Veronika Michalkova, Feziwe Mpondo, Furaha Mramba, Atway Msangi, Nicola Mulder, Grace Murilla, Sarah Mwangi, Loyce Okedi, Sheila Ommeh, Cher-Pheng Ooi, Johnson Ouma, Sumir Panji, Sophie Ravel, Clair Rose, Ryuichi Sakate, Liliane Schoofs, Francesca Scolari, Vineet Sharma, Cheolho Sim, Geoffrey Siwo, Philippe Solano, Dawn Stephens, Yutaka Suzuki, Sing-Hoi Sze, Yeya Touré, Atsushi Toyoda, George Tsiamis, Zhijian Tu, Mark Wamalwa, Florence Wamwiri, Jingwen Wang, Wesley Warren, Junichi Watanabe, Brian Weiss, Judith Willis, Patrick Wincker, Qirui Zhang, Jing-Jiang Zhou
Publication date
2014/4/25
Journal
Science
Volume
344
Issue
6182
Pages
380-386
Publisher
American Association for the Advancement of Science
Description
Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa. Both sexes of adult tsetse feed exclusively on blood and contribute to disease transmission. Notable differences between tsetse and other disease vectors include obligate microbial symbioses, viviparous reproduction, and lactation. Here, we describe the sequence and annotation of the 366-megabase Glossina morsitans morsitans genome. Analysis of the genome and the 12,308 predicted protein–encoding genes led to multiple discoveries, including chromosomal integrations of bacterial (Wolbachia) genome sequences, a family of lactation-specific proteins, reduced complement of host pathogen recognition proteins, and reduced olfaction/chemosensory associated genes. These genome data provide a foundation for research into trypanosomiasis prevention and yield important insights with broad implications for …
Scholar articles
International Glossina Genome Initiative, GM Attardo… - Science, 2014