Authors
Gilbert E D'Alonzo, Robyn J Barst, Stephen M Ayres, Edward H Bergofsky, Bruce H Brundage, Katherine M Detre, Alfred P Fishman, Roberta M Goldring, Berton M Groves, Janet T Kernis, Paul S Levy, Giuseppe G Pietra, Lynne M Reid, John T Reeves, Stuart Rich, Carol E Vreim, George W Williams, Margaret Wu
Publication date
1991/9/1
Journal
Annals of internal medicine
Volume
115
Issue
5
Pages
343-349
Publisher
American College of Physicians
Description
Objective: To characterize mortality in persons diagnosed with primary pulmonary hypertension and to investigate factors associated with survival.
Design: Registry with prospective follow-up.
Setting: Thirty-two clinical centers in the United States participating in the Patient Registry for the Characterization of Primary Pulmonary Hypertension supported by the National Heart, Lung, and Blood Institute.
Patients: Patients (194) diagnosed at clinical centers between 1 July 1981 and 31 December 1985 and followed through 8 August 1988.
Measurements: At diagnosis, measurements of hemodynamic variables, pulmonary function, and gas exchange variables were taken in addition to information on demographic variables, medical history, and life-style. Patients were followed for survival at 6-month intervals.
Main Results: The estimated median survival of these patients was 2. 8 …
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