Authors
Wei Jiang, Michael Babyak, David S Krantz, Robert A Waugh, R Edward Coleman, Michael M Hanson, David J Frid, Steve McNulty, James J Morris, Christopher M O'Connor, James A Blumenthal
Publication date
1996/6/5
Journal
Jama
Volume
275
Issue
21
Pages
1651-1656
Publisher
American Medical Association
Description
Objective
—To assess the clinical significance of mental stress—induced myocardial ischemia in patients with coronary artery disease (CAD).
Design and Setting
—Cohort study in outpatients in a tertiary care teaching hospital assessed at baseline and followed up for up to 5 years.
Subjects
—A total of 126 volunteer patients (112 men, 14 women; mean age, 59 years) with documented CAD and exercise-induced myocardial ischemia.
Outcome Measures
—Patients underwent baseline mental stress and exercise testing using radionuclide ventriculography and 48-hour Holter monitoring. Patients were subsequently contacted by mailed questionnaires or telephone to document cardiac events, including death, nonfatal myocardial infarction, and cardiac revascularization procedures. Logistic regression and Cox proportional hazards models were used to examine the prognostic value of the ischemic measures after …
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Scholar articles
W Jiang, M Babyak, DS Krantz, RA Waugh… - Jama, 1996