Authors
Anja Strangfeld, Martin Schäfer, Milena A Gianfrancesco, Saskia Lawson-Tovey, Jean W Liew, Lotta Ljung, Elsa F Mateus, Christophe Richez, Maria J Santos, Gabriela Schmajuk, Carlo A Scirè, Emily Sirotich, Jeffrey A Sparks, Paul Sufka, Thierry Thomas, Laura Trupin, Zachary S Wallace, Sarah Al-Adely, Javier Bachiller-Corral, Suleman Bhana, Patrice Cacoub, Loreto Carmona, Ruth Costello, Wendy Costello, Laure Gossec, Rebecca Grainger, Eric Hachulla, Rebecca Hasseli, Jonathan S Hausmann, Kimme L Hyrich, Zara Izadi, Lindsay Jacobsohn, Patricia Katz, Lianne Kearsley-Fleet, Philip C Robinson, Jinoos Yazdany, Pedro M Machado
Publication date
2021/7/1
Journal
Annals of the rheumatic diseases
Volume
80
Issue
7
Pages
930-942
Publisher
BMJ Publishing Group Ltd
Description
Objectives
To determine factors associated with COVID-19-related death in people with rheumatic diseases.
Methods
Physician-reported registry of adults with rheumatic disease and confirmed or presumptive COVID-19 (from 24 March to 1 July 2020). The primary outcome was COVID-19-related death. Age, sex, smoking status, comorbidities, rheumatic disease diagnosis, disease activity and medications were included as covariates in multivariable logistic regression models. Analyses were further stratified according to rheumatic disease category.
Results
Of 3729 patients (mean age 57 years, 68% female), 390 (10.5%) died. Independent factors associated with COVID-19-related death were age (66–75 years: OR 3.00, 95% CI 2.13 to 4.22; >75 years: 6.18, 4.47 to 8.53; both vs ≤65 years), male sex (1.46, 1.11 to 1.91), hypertension combined with cardiovascular disease (1.89, 1.31 to 2.73), chronic lung disease (1 …
Total citations
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