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This chapter explores the application of machine learning (ML) in wireless systems, primarily focusing on opportunities in 5G‐Advanced, although not exclusively so. The early sections deliver an introduction, highlighting the role of ML in the wireless technology domain, and an overview of training and inference of models in wireless systems is discussed. The chapter introduces selected examples of use cases in a broad area of wireless systems. Channel coding is a method that adds redundant information to a digital signal before it is passed onto the modulator and transmitted over the radio channel. In a wireless 3GPP‐based mobile network, the Medium Access Control scheduler allocates radio resources in the cell within a carrier and between any aggregated carriers. Radio network planning involves designing the network and optimizing the placement of new base stations and …