Authors
Ulugbek Nurmatov, Sangeeta Dhami, Stefania Arasi, Giovanni Battista Pajno, Montserrat Fernandez‐Rivas, Antonella Muraro, Graham Roberts, Cezmi Akdis, Montserrat Alvaro‐Lozano, Kirsten Beyer, Carsten Bindslev‐Jensen, Wesley Burks, George du Toit, Motohiro Ebisawa, Philippe Eigenmann, Edward Knol, Mika Makela, Kari Christine Nadeau, Liam O'Mahony, Nikolaos Papadopoulos, Lars K Poulsen, Cansin Sackesen, Hugh Sampson, Alexandra Santos, Ronald van Ree, Frans Timmermans, Aziz Sheikh
Publication date
2017/1/1
Source
Allergy
Description
Background
The European Academy of Allergy and Clinical Immunology (EAACI) is developing Guidelines for Allergen Immunotherapy (AIT) for IgE‐mediated Food Allergy. To inform the development of clinical recommendations, we sought to critically assess evidence on the effectiveness, safety and cost‐effectiveness of AIT in the management of food allergy.
Methods
We undertook a systematic review and meta‐analysis that involved searching nine international electronic databases for randomized controlled trials (RCTs) and nonrandomized studies (NRS). Eligible studies were independently assessed by two reviewers against predefined eligibility criteria. The quality of studies was assessed using the Cochrane Risk of Bias tool for RCTs and the Cochrane ACROBAT‐NRS tool for quasi‐RCTs. Random‐effects meta‐analyses were undertaken, with planned subgroup and sensitivity analyses.
Results
We …
Scholar articles
U Nurmatov, S Dhami, S Arasi, GB Pajno… - Allergy, 2017