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Our objective was to improve profitability of catfish farming by demonstrating methods to achieve high levels of survival, feed performance, and efficiency in a commercial farm setting. During 2007, a commercial‐scale in‐pond raceway system (IPRS) was constructed in a 6.0‐acre earthen pond on a catfish farm in west Alabama. The IPRS consisted of six raceways, each stocked with uniform‐sized Channel Catfish Ictalurus punctatus or hybrid catfish (Channel Catfish × Blue Catfish I. furcatus). Co‐cultured fish species (Paddlefish Polyodon spathula and Nile Tilapia Oreochromis niloticus) were stocked and harvested in the outside area of the pond containing the IPRS. Results from the 2008 production season were used to project 12 months of production from stocking either Channel Catfish or hybrid catfish in the IPRS. In addition, Channel Catfish production in traditional ponds was monitored from 2005 to 2009 on …