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The most similar crash test was identified for each of 100 Crash Injury Research and Engineering Network (CIREN) cases. To quantify the best comparison pairs, a Similarity Scoring Methodology (SSM) with 12 parameters was developed. The results showed 18 comparisons with ‘low’ (0–6 points), 72 with ‘medium’ (7–9 points) and 10 with ‘high’ (10–12 points) similarity scores. Thirty-nine CIREN cases received a similarity point for deltaV (within range: ±16.1 kph [10 mph]). Thirty-seven CIREN cases had a lower deltaV than the crash test. For occupant parameters, seating position and airbag deployment received similarity points most frequently (86% each). Occupant height and weight received points least frequently (41% and 20%, respectively), typically because CIREN occupants were shorter and heavier compared with Anthropometric Test Device (ATD) sizes. This work establishes a standard SSM to be used …