Authors
Keith F Stringer, C James Ingles, Jack Greenblatt
Publication date
1990/6/28
Journal
Nature
Volume
345
Issue
6278
Pages
783-786
Publisher
Nature Publishing Group UK
Description
The potent transactivation domain of the herpes simplex virion protein VP16 was used as a column ligand for affinity chromatography. VP16 binds strongly and highly selectively to the human and yeast TATA box-binding factors. Our results imply that the principal target for acidic activation domains is the TATA-box factor TFIID.
Total citations
Scholar articles
KF Stringer, CJ Ingles, J Greenblatt - Nature, 1990