Authors
Manoj B Gawande, Vasco DB Bonifácio, Rafael Luque, Paula S Branco, Rajender S Varma
Publication date
2013
Source
Chemical Society Reviews
Volume
42
Issue
12
Pages
5522-5551
Publisher
Royal Society of Chemistry
Description
Catalyst-free reactions developed during the last decade and the latest developments in this emerging field are summarized with a focus on catalyst-free reactions in-water and on-water. Various named reactions, multi-component reactions and the synthesis of heterocyclic compounds are discussed including the use of various energy input systems such as microwave- and ultrasound irradiation, among others. Organic chemists and the practitioners of this art both in academia and industry hopefully will continue to design benign methodologies for organic synthesis in aqueous media under catalyst-free conditions by using alternative energy inputs based on fundamental principles.
Scholar articles
Benign by design: catalyst-free in-water, on-water green chemical methodologies in organic synthesis
MB Gawande, VDB Bonifácio, R Luque, PS Branco… - Chemical Society Reviews, 2013