Authors
Jens C Pruessner, Clemens Kirschbaum, Gunther Meinlschmid, Dirk H Hellhammer
Publication date
2003/10/1
Journal
Psychoneuroendocrinology
Volume
28
Issue
7
Pages
916-931
Publisher
Pergamon
Description
Study protocols in endocrinological research and the neurosciences often employ repeated measurements over time to record changes in physiological or endocrinological variables. While it is desirable to acquire repeated measurements for finding individual and group differences with regard to response time and duration, the amount of data gathered often represents a problem for the statistical analysis. When trying to detect possible associations between repeated measures and other variables, the area under the curve (AUC) is routinely used to incorporate multiple time points. However, formulas for computation of the AUC are not standardized across laboratories, and existing differences are usually not presented when discussing results, thus causing possible variability, or incompatibility of findings between research groups. In this paper, two formulas for calculation of the area under the curve are presented …
Total citations
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