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Landscape level variability of structure and tree species diversity was analyzed in a tropical deciduous forest at Chamela, Mexico. Trees with DBH≥ 5 cm were sampled in 21 0.24 ha plots (5.04 ha in total) distributed among six different morpho-pedological land units. Average density was 1,385 individuals ha-1, basal area 15.9 m2 ha-1, and canopy height 6.8 m. Trunks with DBH≤ 14 cm accounted for 90% of the entire set. A total of 148 species, 102 genera, and 43 families were recorded. Seventy percent of all species were poorly represented (< 10 individuals ha-1). A Principal Component Analysis (PCA) based on structure and diversity variables showed that plots from the same morpho-pedological land unit were not always located close to each other along the two first axes, but a further PCA based on dominant species clearly divided two groups of plots. Although canopy structure and tree species diversity varied continuously across the landscape, β-diversity (evaluated through species similarity between plot pairs) and the identities of dominant species exhibited the clearest distinction. The dichotomy between granitic vs. non-granitic lithology was the condition most clearly related with a lower similarity in species composition and the strongest contrast in the dominant species group.