Authors
Jeremy T Howard, Shihui Jiao, Francesco Tiezzi, Yijian Huang, Kent A Gray, Christian Maltecca
Publication date
2015/12
Journal
Bmc Genetics
Volume
16
Pages
1-11
Publisher
BioMed Central
Description
Background
Feed intake and growth are economically important traits in swine production. Previous genome wide association studies (GWAS) have utilized average daily gain or daily feed intake to identify regions that impact growth and feed intake across time. The use of longitudinal models in GWAS studies, such as random regression, allows for SNPs having a heterogeneous effect across the trajectory to be characterized. The objective of this study is therefore to conduct a single step GWAS (ssGWAS) on the animal polynomial coefficients for feed intake and growth.
Results
Corrected daily feed intake (DFI Adj ) and average daily weight measurements (DBW Avg ) on 8981 (n = 525,240 observations) and 5643 (n = 283,607 observations) animals were utilized in a random regression …
Total citations
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