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Business process analysis and process mining, particularly within the health care domain, remain under-utilized. Applied research that employs such techniques to routinely collected health care data enables stakeholders to empirically investigate care as it is delivered by different health providers. However, cross-organizational mining and the comparative analysis of processes present a set of unique challenges in terms of ensuring population and activity comparability, visualizing the mined models, and interpreting the results. Without addressing these issues, health providers will find it difficult to use process mining insights, and the potential benefits of evidence-based process improvement within health will remain unrealized. In this article, we present a brief introduction on the nature of health care processes, a review of process mining in health literature, and a case study conducted to explore and learn how …