Authors
Clementine M Boutry, Levent Beker, Yukitoshi Kaizawa, Christopher Vassos, Helen Tran, Allison C Hinckley, Raphael Pfattner, Simiao Niu, Junheng Li, Jean Claverie, Zhen Wang, James Chang, Paige M Fox, Zhenan Bao
Publication date
2019/1
Journal
Nature biomedical engineering
Volume
3
Issue
1
Pages
47-57
Publisher
Nature Publishing Group UK
Description
The ability to monitor blood flow is critical to patient recovery and patient outcomes after complex reconstructive surgeries. Clinically available wired implantable monitoring technology requires careful fixation for accurate detection and needs to be removed after use. Here, we report the design of a pressure sensor, made entirely of biodegradable materials and based on fringe-field capacitor technology, for measuring arterial blood flow in both contact and non-contact modes. The sensor is operated wirelessly through inductive coupling, has minimal hysteresis, fast response times, excellent cycling stability, is highly robust, allows for easy mounting and eliminates the need for removal, thus reducing the risk of vessel trauma. We demonstrate the operation of the sensor with a custom-made artificial artery model and in vivo in rats. This technology may be advantageous in real-time post-operative monitoring of blood …
Total citations
2019202020212022202320244410715013515097
Scholar articles
CM Boutry, L Beker, Y Kaizawa, C Vassos, H Tran… - Nature biomedical engineering, 2019