Authors
Kimberly Y Smith, Camlin Tierney, Katie Mollan, Charles S Venuto, Chakra Budhathoki, Qing Ma, Gene D Morse, Paul Sax, David Katzenstein, Catherine Godfrey, Margaret Fischl, Eric S Daar, Ann C Collier, AIDS Clinical Trials Group 5202 Study Team, Hector H Bolivar, Sandra Navarro, Susan L Koletar, Diane Gochnour, Edward Seefried, Julie Hoffman, Judith Feinberg, Michelle Saemann, Kristine Patterson, Donna Pittard, David Currin, Kerry Upton, Michael Saag, Graham Ray, Steven Johnson, Bartolo Santos, Connie A Funk, Michael Morgan, Brenda Jackson, Pablo Tebas, Aleshia Thomas, Ge-Youl Kim, Michael K Klebert, Jorge L Santana, Santiago Marrero, Jane Norris, Sandra Valle, Gary Matthew Cox, Martha Silberman, Sadia Shaik, Ruben Lopez, Margie Vasquez, Demetre Daskalakis, Christina Megill, Jessica Shore, Babafemi Taiwo, Mitchell Goldman, Molly Boston, Jeffrey Lennox, Carlos del Rio, Timothy W Lane, Kim Epperson, Annie Luetkemeyer, Mary Payne, Barbara Gripshover, Dawn Antosh, Jane Reid, Mary Adams, Sheryl S Storey, Shelia B Dunaway, Joel Gallant, Ilene Wiggins, Kimberly Y Smith, Joan A Swiatek, Joseph Timpone, Princy Kumar, Ardis Moe, Maria Palmer, Jon Gothing, Joanne Delaney, Kim Whitely, Ann Marie Anderson, Scott M Hammer, Michael T Yin, Mamta Jain, Tianna Petersen, Roberto Corales, Christine Hurley, Keith Henry, Bette Bordenave, Amanda Youmans, Mary Albrecht, Richard B Pollard, Abimbola Olusanya, Paul R Skolnik, Betsy Adams, Karen T Tashima, Helen Patterson, Michelle Ukwu, Lauren Rogers, Henry H Balfour, Kathy A Fox, Susan Swindells, Frances Van Meter, Gregory Robbins, Nicole Burgett-Yandow, Charles E Davis, Colleen Boyce, William A O'Brien, Gerianne Casey, Gene D Morse, Chiu-Bin Hsaio, Jeffrey L Meier, Jack T Stapleton, Donna Mildvan, Manuel Revuelta, David Currin, Wafaa El Sadr, Avelino Loquere, Nyef El-Daher, Tina Johnson, Robert Gross, Kathyrn Maffei, Valery Hughes, Glenn Sturge, Deborah McMahon, Barbara Rutecki, Michael Wulfsohn, Andrew Cheng, Lynn Dix, Qiming Liao
Publication date
2014/2/15
Journal
Clinical infectious diseases
Volume
58
Issue
4
Pages
555-563
Publisher
Oxford University Press
Description
Background. We aimed to evaluate treatment responses to atazanavir plus ritonavir (ATV/r) or efavirenz (EFV) in initial antiretroviral regimens among women and men, and determine if treatment outcomes differ by sex.
Methods. We performed a randomized trial of open-label ATV/r or EFV combined with abacavir/lamivudine (ABC/3TC) or tenofovir/emtricitabine (TDF/FTC) in 1857 human immunodeficiency virus type 1–infected, treatment-naive persons enrolled between September 2005 and November 2007 at 59 sites in the United States and Puerto Rico. Associations of sex with 3 primary study endpoints of time to virologic failure, safety, and tolerability events were analyzed using Cox proportional hazards models. Model-based population pharmacokinetic analysis was performed using nonlinear mixed effects modeling (NONMEM version VII …
Scholar articles
KY Smith, C Tierney, K Mollan, CS Venuto… - Clinical infectious diseases, 2014