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Objectives:

Balance and gait problems have repeatedly been mentioned in case descriptions of patients infected with Human Immunodeficiency Virus (HIV-1). Objective evidence of these problems has rarely been reported, however. Furthermore, the extent to which balance and gait are influenced by antiretroviral medications or comorbid psychiatric disorders has rarely been examined.

Design:

The study compared 78 HIV-1 seronegative volunteers to 28 HIV/AIDS patients receiving no antiretroviral therapy, 25 patients receiving only nucleoside analogue therapy, and 37 patients receiving Highly Active Antiretroviral Therapy (HAART).

Methods:

The dependent measures included Equilibrium Quotient scores recorded during 3 subtests of the Sensory Organization Test (SOT), the number of falls during each subtest, the functional base of support, gait speed and cadence, single leg balance time, proximal strength, and …