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With new advances in ambulatory monitoring new challenges appear due to degradation in signal quality and limitations in hardware requirements. Existing signal analysis methods should be re-evaluated in order to adapt to the restrictive requirements of these new applications. With this motivation, we chose a robust beat detection algorithm and optimized it further to be running in an embedded platform within a cardiac monitoring sensor node. The algorithm was designed in floating point in Matlab and evaluated in order to study its performance under a wide range of conditions. The initial PC version of the algorithm obtained a good performance under a wide variety of conditions (Se = 99.65% and + P = 99.79% on the MIT/BIH arrhythmia database and Se = 99.88%, + P = 99.93% on our own database with ambulatory data). In this study, the algorithm is adapted and further optimized to work in real time on an …