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Objectives

The aim of this study was to assess changes in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG) seroprevalence among children and adolescents in Delhi, India from January 2021 to October 2021

Methods

This was a repeated cross-sectional analysis of participants aged 5 to 17 years from 2 SARS-CoV-2 seroprevalence surveys conducted in Delhi, India during January 2021 and September to October 2021. Anti-SARS-CoV-2 IgG antibodies were detected by using the VITROS assay (90% sensitivity, 100% specificity).

Results

The seroprevalence among 5-to 17-year-old school-age children and adolescents increased from 52.8%(95% confidence interval [CI], 51.3%− 54.3%) in January 2021 to 81.8%(95% CI, 80.9%− 82.6%) in September to October 2021. The assay-adjusted seroprevalence was 90.8%(95% CI, 89.8%− 91.7%). Seropositivity positively …