Authors
Jun-Jie Xu, Min Zhang, Katherine Brown, Kathleen Reilly, Hailong Wang, Qinghai Hu, Haibo Ding, Zhenxing Chu, Tristan Bice, Hong Shang
Publication date
2010/7/1
Journal
Sexually transmitted diseases
Volume
37
Issue
7
Pages
432-439
Publisher
LWW
Description
Background:
Cross-sectional studies have found a high prevalence of syphilis and HIV infection among men who have sex with men (MSM) in China.
Methods:
A total of 218 HIV-negative MSM participated in this prospective cohort study. Interviewer-administered questionnaires were completed, and blood samples were obtained for HIV and syphilis testing, both upon enrollment and at 12-month follow-up.
Results:
Of enrolled participants, 56%(122) were retained for the full 12-month follow-up period. The cohort had an HIV incidence density of 5.4 (95% CI: 2.0–11.3)/100 person-year (PY) and a syphilis incidence density of 38.5 (95% CI: 27.7–50.2)/100 PY. Having syphilis (odds ratio [OR]: 11.4, 95% CI: 1.2–104.7) and more than 5 male sexual partners within the past 12 months (OR: 6.5, 95% CI: 1.1–39.8) were independent risk factors for HIV seroconversion (each P< 0.05). Being married (OR: 3.5, 95% CI: 1.4–8.2 …
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