Authors
Sérgio Luiz Pinheiro, Ana Cláudia Bonadiman, Ana Luiza dos Anjos Borges Lemos, Bruna Maki Annicchino, Bruna Segatti, Daniel Sartorelli Pucca, Priscila Tessaro Dutra, Roberta Mariano de Carvalho e Silva, Frederico Leal
Publication date
2019/3/1
Journal
Photobiomodulation, photomedicine, and laser surgery
Volume
37
Issue
3
Pages
142-150
Publisher
Mary Ann Liebert, Inc., publishers
Description
Objective: To evaluate the use of photobiomodulation therapy (PBM-T) in patients undergoing chemotherapy and/or radiotherapy and affected by oral mucositis (OM).
Background: Few clinical studies have evaluated PBM-T, particularly in combination with photodynamic therapy (PDT), for the treatment of OM.
Methods: Thirty-one patients were divided by convenience into two groups. One received PBM-T (n = 17) alone, consisting of low-intensity laser (LIL) irradiation (wavelength 660 nm, continuous mode, spot energy 4 J, energy density 142 J/cm2, irradiation time 40 s per spot), once weekly for 4 weeks. The other (n = 14) received a combination of PBM-T and PDT, with curcumin as photosensitizer. Patients were instructed to rinse their mouth with 20 mL of curcumin solution for 5 min. The oral cavity was irradiated with a blue light-emitting diode (power 1200 mV, wavelength 468 nm) for 5 min. LIL …
Scholar articles
SL Pinheiro, AC Bonadiman, ALA Borges Lemos… - Photobiomodulation, photomedicine, and laser surgery, 2019