Authors
Bruce Ovbiagele, Mathew J Reeves, Mojdeh Nasiri, S Claiborne Johnston, Philip M Bath, Gustavo Saposnik, VISTA-Acute Collaboration Steering Committee
Publication date
2014/7/1
Journal
JAMA neurology
Volume
71
Issue
7
Pages
848-854
Publisher
American Medical Association
Description
Importance
The Stroke Prognostication using Age and the NIH Stroke Scale index, created by combining age in years plus a National Institutes of Health (NIH) Stroke Scale score of 100 or higher (and hereafter referred to as the SPAN-100 index), is a simple risk score for estimating clinical outcomes for patients with acute ischemic stroke (AIS). The association between this index and response to intravenous thrombolysis for AIS has not been properly evaluated.
Objective
To assess the relationship between SPAN-100 index status and outcome following treatment with intravenous thrombolysis for AIS.
Design, Setting, and Participants
Using the Virtual International Stroke Trials Archive (VISTA) database, an international repository of clinical trials data, we assessed the SPAN-100 index among 7093 patients with AIS who participated in 4 clinical trials from 2000 to 2006. The SPAN-100 index is considered positive if the …
Scholar articles
B Ovbiagele, MJ Reeves, M Nasiri, SC Johnston… - JAMA neurology, 2014