Authors
Wayne Smith, Jacqueline Assink, Ronald Klein, Paul Mitchell, Caroline CW Klaver, Barbara EK Klein, Albert Hofman, Susan Jensen, Jie Jin Wang, Paulus TVM de Jong
Publication date
2001/4/1
Journal
Ophthalmology
Volume
108
Issue
4
Pages
697-704
Publisher
Elsevier
Description
OBJECTIVE
To assess the prevalence and potential risk factors for late age-related macular degeneration (AMD) in three racially similar populations from North America, Europe, and Australia.
DESIGN
Combined analysis of population-based eye disease prevalence data.
PARTICIPANTS
There were 14,752 participants with gradable photographs from the Beaver Dam Eye Study (n = 4756), Rotterdam Study (n = 6411), and Blue Mountains Eye Study (n = 3585).
MAIN OUTCOME MEASURES
AMD diagnosis was made from masked grading of stereo macular photographs. Final classification of AMD cases was agreed by consensus between study investigators.
RESULTS
AMD prevalence was strongly age related. Overall, AMD was present in 0.2% of the combined population aged 55 to 64 years, rising to 13% of the population older than 85 years. Prevalence of neovascular AMD (NV) increased from 0.17% among …
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Scholar articles
W Smith, J Assink, R Klein, P Mitchell, CCW Klaver… - Ophthalmology, 2001