Authors
Ryan W Loney, Shankar B Rananavare, Stephen B Hall
Publication date
2011/2/2
Journal
Biophysical Journal
Volume
100
Issue
3
Pages
633a-634a
Publisher
Elsevier
Description
Wednesday, March 9, 2011 633a the steeper slopes reflected later time or lower g. Adsorption at constant g and to preexisting films showed that the steeper slope depended on g rather than time, indicating that the acceleration resulted from changes in the film rather than in the adsorbing material. Compositional studies tested how removing cholesterol, the anionic phospholipids, and the hydrophobic proteins affected the late acceleration. Only the absence of the proteins eliminated the late adsorption. Vesicles of phospholipid with dioleoyl phosphatidylethanolamine, however, which, like the surfactant proteins, promotes fusion between vesicles, also demonstrated the accelerated late adsorption. These results suggest that the late acceleration occurs when vesicles that adsorb by fusion with the nascent film can interact more readily with a more densely packed monolayer.(Small angle x-ray diffraction studies …
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