Authors
Gina EC Charnley, Sebastian Yennan, Chinwe Ochu, Ilan Kelman, Katy AM Gaythorpe, Kris A Murray
Publication date
2023/5/1
Journal
PLOS Neglected Tropical Diseases
Volume
17
Issue
5
Pages
e0011312
Publisher
Public Library of Science
Description
Background
Understanding and continually assessing the achievability of global health targets is key to reducing disease burden and mortality. The Global Task Force on Cholera Control (GTFCC) Roadmap aims to reduce cholera deaths by 90% and eliminate the disease in twenty countries by 2030. The Roadmap has three axes focusing on reporting, response and coordination. Here, we assess the achievability of the GTFCC targets in Nigeria and identify where the three axes could be strengthened to reach and exceed these goals.
Methodology/Principal findings
Using cholera surveillance data from Nigeria, cholera incidence was calculated and used to model time-varying reproduction number (R). A best fit random forest model was identified using R as the outcome variable and several environmental and social covariates were considered in the model, using random forest variable importance and correlation clustering. Future scenarios were created (based on varying degrees of socioeconomic development and emissions reductions) and used to project future cholera transmission, nationally and sub-nationally to 2070. The projections suggest that significant reductions in cholera cases could be achieved by 2030, particularly in the more developed southern states, but increases in cases remain a possibility. Meeting the 2030 target, nationally, currently looks unlikely and we propose a new 2050 target focusing on reducing regional inequities, while still advocating for cholera elimination being achieved as soon as possible.
Conclusion/Significance
The 2030 targets could potentially be reached by 2030 in some parts of Nigeria, but …
Total citations
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