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Background

Left ventricular hypertrophy (LVH) is an independent predictor of morbidity and mortality in chronic hemodialysis (CHD) patients. It remains unclear whether efforts to correct fluid overload in young CHD can reverse LVH. This prospective single-center cohort study evaluated left ventricular masses index (LVMI) evolution in fluid overloaded young CHD patients with or without water-sodium control.

Methods

A total of 106 young patients aged between 22 and 44 years on CHD were enrolled in this prospective, control study. Patients were divided into three groups according to the percentage of interdialytic weight gain (PIDWG (%)= 100%×(predialysis weight-dry weight)/dry weight) at baseline. Thirty-six patients with PIDWG more than 5% received health education to restrict water-sodium intake strictly (Group I). Other 36 patients with comparable fluid status levels (the PIDWG more than 5%) did not receive …