Authors
Stefan Schandelmaier, Matthias Briel, Ramon Saccilotto, Kelechi K Olu, Armon Arpagaus, Lars G Hemkens, Alain J Nordmann
Publication date
2017
Journal
Cochrane Database of Systematic Reviews
Issue
6
Publisher
John Wiley & Sons, Ltd
Description
Background
Nicotinic acid (niacin) is known to decrease LDL‐cholesterol, and triglycerides, and increase HDL‐cholesterol levels. The evidence of benefits with niacin monotherapy or add‐on to statin‐based therapy is controversial.
Objectives
To assess the effectiveness of niacin therapy versus placebo, administered as monotherapy or add‐on to statin‐based therapy in people with or at risk of cardiovascular disease (CVD) in terms of mortality, CVD events, and side effects.
Scholar articles
S Schandelmaier, M Briel, R Saccilotto, KK Olu… - Cochrane Database of Systematic Reviews, 2017