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This paper proposes a novel probabilistic methodology for estimating the life-cycle reliability of existing reinforced concrete (RC) bridges under multiple hazards. The life-cycle reliability of an RC bridge pier under seismic and airborne chloride hazards is compared to that of a bridge girder under traffic and airborne chloride hazards. When conducting a life-cycle reliability assessment of existing RC bridges, observational data from inspections can provide the corrosion level in reinforcement steel. Random variables related with the prediction of time-variant steel weight loss can be updated based on the inspection results using Sequential Monte Carlo Simulation (SMCS). This paper presents a novel procedure for identifying the hazards that most threaten the structural safety of existing RC bridges, as well as the structural components with the lowest reliability when these bridges are exposed to multiple hazards. The …