Authors
Eric O Kwon, Brett S Carver, Mark E Snyder, Paul Russo
Publication date
2007/2
Journal
BJU international
Volume
99
Issue
2
Pages
286-289
Publisher
Blackwell Publishing Ltd
Description
OBJECTIVE
To evaluate the clinical outcome of patients undergoing partial nephrectomy (PN) for renal cortical tumours who had a positive surgical margin (SM), as recent studies have shown that a minimal SM is required to achieve equivalent disease‐free survival (DFS).
PATIENTS AND METHODS
Between 1989 and 2005, 777 PNs were performed at the authors’ institution. Clinical and pathology data were obtained from our prospective surgical database after obtaining institutional review board approval. Variables were analysed in a logistic regression model to determine predictors of positive SMs. The clinical outcome was reported for local recurrence and distant metastasis and analysed using the log‐rank test.
RESULTS
Of the 777 PNs, the SM status was documented in 770; the SMs were positive in 57 of 770 (7%). Positive SMs occurred in 33 of 423 (8%) patients with tumours of high malignant potential …
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