Authors
Philippe Ryvlin, Lina Nashef, Samden D Lhatoo, Lisa M Bateman, Jonathan Bird, Andrew Bleasel, Paul Boon, Arielle Crespel, Barbara A Dworetzky, Hans Høgenhaven, Holger Lerche, Louis Maillard, Michael P Malter, Cecile Marchal, Jagarlapudi MK Murthy, Michael Nitsche, Ekaterina Pataraia, Terje Rabben, Sylvain Rheims, Bernard Sadzot, Andreas Schulze-Bonhage, Masud Seyal, Elson L So, Mark Spitz, Anna Szucs, Meng Tan, James X Tao, Torbjörn Tomson
Publication date
2013/10/1
Journal
The Lancet Neurology
Volume
12
Issue
10
Pages
966-977
Publisher
Elsevier
Description
Background
Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in people with chronic refractory epilepsy. Very rarely, SUDEP occurs in epilepsy monitoring units, providing highly informative data for its still elusive pathophysiology. The MORTEMUS study expanded these data through comprehensive evaluation of cardiorespiratory arrests encountered in epilepsy monitoring units worldwide.
Methods
Between Jan 1, 2008, and Dec 29, 2009, we did a systematic retrospective survey of epilepsy monitoring units located in Europe, Israel, Australia, and New Zealand, to retrieve data for all cardiorespiratory arrests recorded in these units and estimate their incidence. Epilepsy monitoring units from other regions were invited to report similar cases to further explore the mechanisms. An expert panel reviewed data, including video electroencephalogram (VEEG) and electrocardiogram material at …
Total citations
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