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Based on a 2 year seismic record from a local network, we characterize the deformation of the seismogenic crust of the Pamir in the northwestern part of the India‐Asia collision zone. We located more than 6000 upper crustal earthquakes in a regional 3‐D velocity model. For 132 of these events, we determined source mechanisms, mostly through full waveform moment tensor inversion of locally and regionally recorded seismograms. We also produced a new and comprehensive neotectonic map of the Pamir, which we relate to the seismic deformation. Along Pamir's northern margin, where GPS measurements show significant shortening, we find thrust and dextral strike‐slip faulting along west to northwest trending planes, indicating slip partitioning between northward thrusting and westward extrusion. An active, north‐northeast trending, sinistral transtensional fault system dissects the Pamir's interior, connecting …