Authors
Raveendhara R Bannuru, Christopher H Schmid, David M Kent, Elizaveta E Vaysbrot, John B Wong, Timothy E McAlindon
Publication date
2015/1/6
Source
Annals of internal medicine
Volume
162
Issue
1
Pages
46-54
Publisher
American College of Physicians
Description
Background
The relative efficacy of available treatments of knee osteoarthritis (OA) must be determined for rational treatment algorithms to be formulated.
Purpose
To examine the efficacy of treatments of primary knee OA using a network meta-analysis design, which estimates relative effects of all treatments against each other.
Data Sources
MEDLINE, EMBASE, Web of Science, Google Scholar, Cochrane Central Register of Controlled Trials from inception through 15 August 2014, and unpublished data.
Study Selection
Randomized trials of adults with knee OA comparing 2 or more of the following: acetaminophen, diclofenac, ibuprofen, naproxen, celecoxib, intra-articular (IA) corticosteroids, IA hyaluronic acid, oral placebo, and IA placebo.
Data Extraction
Two reviewers …
Total citations
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