Authors
Waseem Abu-Ashour, Laurie Twells, James Valcour, Amy Randell, Jennifer Donnan, Patricia Howse, John-Michael Gamble
Publication date
2017/5/1
Source
BMJ Open Diabetes Research and Care
Volume
5
Issue
1
Pages
e000336
Publisher
BMJ Specialist Journals
Description
Objective
To quantify the association between diabetes and the risk of incident infections by conducting a systematic review and meta-analysis.
Research design and methods
Two reviewers independently screened articles identified from PubMed, EMBASE, Cochrane Library, IPA, and Web of Science databases. Cohort studies (CS) or case–control studies (CCS) evaluating the incidence of infections in adults with diabetes were included. Infections were classified as: skin and soft tissue, respiratory, blood, genitourinary, head and neck, gastrointestinal, bone, viral, and non-specified infections. Study quality was assessed using the Newcastle-Ottawa Quality Assessment Scale. Summary crude and adjusted OR with 95% CIs were calculated using random effects models, stratified by study design. Heterogeneity was measured using the I2statistic and explored using subgroup analyses.
Results
A total of 345 (243 CS …
Total citations
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